3-Bromofuran-2-carboxylic acid → HCID 9901891, compound

HRID 2114934Notes

Reaction equation

HRID 2114934 reaction equation
[Br:1][C:2]1[CH:6]=[CH:5][O:4][C:3]=1[C:7]([OH:9])=O.[Cl:10][C:11]1[CH:12]=[CH:13][C:14]([C:17](=[N:19]O)[NH2:18])=[N:15][CH:16]=1>>[Br:1][C:2]1[CH:6]=[CH:5][O:4][C:3]=1[C:7]1[O:9][N:19]=[C:17]([C:14]2[CH:13]=[CH:12][C:11]([Cl:10])=[CH:16][N:15]=2)[N:18]=1

Participants

3

Reactant 2

HCID 6054793-Bromofuran-2-carboxylic acidHCID 136279893HCID 136279893, compound

Product 1

HCID 9901891HCID 9901891, compound

Procedure

The title compound was prepared from 3-bromo-furan-2-carboxylic acid (381.7 mg, 2.00 mmol) and 5-chloro-pyridine-2-amidoxime (343 mg, 2.00 mmol), similar to Example 70, and yielded 353 mg (54%) of white solid.

Sources & evidence

ORD record
ord-fe254b57b771471e96dd0e7d13497506
Source dataset
uspto-grants-2008_10
Patent number
US07435750B2

Reaction notes

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