4-chloro-N'-hydroxybenzenecarboximidamide → 5-(3-Bromo-furan-2-yl)-3-(4-chloro-phenyl)-[1,2,4]oxadiazole

Participants

Reaction Steps

The title compound was prepared from 4-chlorobenzamidoxime (479 mg, 2.29 mmol) and 3-bromo-furan-2-carbonyl chloride (390 mg, 2.29 mmol) similar to Example 16, and yielded 570 mg (81%) of white solid. 1H NMR (CDCl3): 8.13 (dd, J=8.80, 2.20 Hz, 2H), 7.67 (d, J=1.92 Hz, 1H), 7.49 (dd, J=8.79, 2.20 Hz, 2H), 6.75 (d, J=1.92 Hz, 1H).

Provenance & Evidence