Benzamidine, hydrochloride → HCID 22147891, compound

HRID 2114943Notes

Reaction equation

HRID 2114943 reaction equation
Cl.[C:2]([NH2:10])(=[NH:9])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[Cl:11][C:12]1[CH:16]=[CH:15][S:14][C:13]=1[C:17]([NH:19]N)=O>>[Cl:11][C:12]1[CH:16]=[CH:15][S:14][C:13]=1[C:17]1[NH:19][N:10]=[C:2]([C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=2)[N:9]=1

Participants

3

Reactant 2

HCID 80289Benzamidine, hydrochlorideHCID 23570764HCID 23570764, compound

Product 1

HCID 22147891HCID 22147891, compound

Procedure

The title compound was prepared from benzamidine hydrochloride and 3-chloro-thiophene-2-carboxylic acid hydrazide by a procedure similar to Example 88b as a yellowish solid (0.141 g, 37%). 1H NMR (DMSO-d6): 8.04 (d, J=9.6 Hz, 2H), 7.80 (d, J=6.0 Hz, 1H), 7.55 (d, J=7.80 Hz, 3H), 7.19 (d, J=5.70 Hz, 1H).

Sources & evidence

ORD record
ord-7eaee4100d7c432bba999076692425ed
Source dataset
uspto-grants-2008_10
Patent number
US07435750B2

Reaction notes

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