3-methylbenzenecarboximidamide Hydrochloride → HCID 22147857, compound

HRID 2114945Notes

Reaction equation

HRID 2114945 reaction equation
Cl.[CH3:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=1)[C:6]([NH2:8])=[NH:7].[Cl:12][C:13]1[CH:17]=[CH:16][S:15][C:14]=1[C:18]([NH:20]N)=O>>[Cl:12][C:13]1[CH:17]=[CH:16][S:15][C:14]=1[C:18]1[NH:20][N:8]=[C:6]([C:5]2[CH:9]=[CH:10][CH:11]=[C:3]([CH3:2])[CH:4]=2)[N:7]=1

Participants

3

Reactant 2

HCID 28007013-methylbenzenecarboximidamide HydrochlorideHCID 23570764HCID 23570764, compound

Product 1

HCID 22147857HCID 22147857, compound

Procedure

The title compound was prepared from 3-methyl-benzamidine hydrochloride and 3-chloro-thiophene-2-carboxylic acid hydrazide by a procedure similar to Example 88b as a yellow solid (0.013 g, 5.6%). 1H NMR (CD3OD): 7.75 (s, 1H), 7.69 (d, J=5.7 Hz, 1H), 7.4 (d, J=5.7 Hz, 1H), 7.24 (m, 2H), 6.97 (d, J=6.3 Hz, 1H), 3.10 (s, 3H).

Sources & evidence

ORD record
ord-53c79c982940456abe8273ca4a4049e2
Source dataset
uspto-grants-2008_10
Patent number
US07435750B2

Reaction notes

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