HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloronicotinoyl Chloride → HCID 22147922, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloronicotinoyl Chloride | HCID 2782165 | — |
| Reactant | HCID 22147914 | HCID 22147914 | — |
| Reactant | 2-(3-Chloro-thiophen-2-yl)-2-oxo-1-ethylamine hydrochloride | HCID 69249884 | — |
| Product | HCID 22147922 | HCID 22147922 | — |
Reaction Steps
6-Chloro-N-[2-(3-chloro-thiphen-2-yl)-2-oxo-ethyl]-nicotinamide: The title compound was prepared from 2-(3-chloro-thiophen-2-yl)-2-oxo-1-ethylamine hydrochloride and 6-chloronicotinoyl chloride by a procedure similar to Example 98a as a white solid (0.044 g, 30%). 1H NMR (CD3OD): 8.74 (d, J=8.74 Hz, 1H), 8.13 (d, J=6.3 Hz, 1H), 7.79 (d, J=5.4 Hz, 1H), 7.48 (d, J=9.0 Hz, 1H), 7.07 (d, J=5.4 Hz, 1H), 4.75 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435750B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-e183a31c6a2543ed839c4ed7a7074e1e |
| Source note | uspto-grants-2008_10 |