1H-Indazol-6-amine → HCID 69100281, compound

HRID 2114981Notes

Reaction equation

HRID 2114981 reaction equation
[NH2:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[N:7][NH:8]2)=[CH:4][CH:3]=1.[F:11][C:12]1[CH:29]=[CH:28][C:15]([CH2:16][CH:17]2[CH2:22][CH2:21][N:20]([C:23](=[O:27])[C:24](O)=[O:25])[CH2:19][CH2:18]2)=[CH:14][CH:13]=1>C(OCC)C>[F:11][C:12]1[CH:29]=[CH:28][C:15]([CH2:16][CH:17]2[CH2:18][CH2:19][N:20]([C:23](=[O:27])[C:24]([NH:1][C:2]3[CH:10]=[C:9]4[C:5]([CH:6]=[N:7][NH:8]4)=[CH:4][CH:3]=3)=[O:25])[CH2:21][CH2:22]2)=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 814231H-Indazol-6-amineHCID 51342220[4-(4-Fluorobenzyl)piperidin-1-yl](oxo)acetic acid

Product 1

HCID 69100281HCID 69100281, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 6-aminoindazol (Aldrich) and [4-(4-fluoro-benzyl)-piperidin-1-yl]-oxo-acetic acid (Example 1b) according to the method described in Example 2. Melting Point: 162-164° C. (diethylether)

Sources & evidence

ORD record
ord-0841ee6bacd3434f9685903f3f6f9580
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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