HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-amino-1,3-benzoxazol-2(3H)-one → HCID 10273343, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-amino-1,3-benzoxazol-2(3H)-one | HCID 826989 | — |
| Reactant | HCID 69100024 | HCID 69100024 | — |
| Product | HCID 10273343 | HCID 10273343 | — |
Reaction Steps
The title compound is prepared from [4-(4-chloro-phenoxy)-piperidin-1-yl]-oxo-acetic acid (Example 29d) and 6-amino-3H-benzoxazol-2-one according to the method described in Example 2. The filtered crystals are purified by column chromatography using Kieselgel 60 (Merck) as adsorbent and toluene:methanol=4:1 as eluent. Melting Point: 242-244° C. (isopropanol)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-eb92c84e40284eea83088864e5cc1519 |
| Source note | uspto-grants-2008_10 |