6-amino-3,4-dihydro-2H-1,4-benzoxazin-3-one → 2-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(3-oxo-3,4-dihydro-2H-benzo [1,4]oxazin-6-yl)-acetamide

HRID 2115007노트

반응식

HRID 2115007 반응식
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][CH2:9][C:8](=[O:11])[NH:7][C:6]=2[CH:12]=1.[CH2:13]([CH:20]1[CH2:25][CH2:24][N:23]([C:26](=[O:30])[C:27](O)=[O:28])[CH2:22][CH2:21]1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(OCC)C>[CH2:13]([CH:20]1[CH2:21][CH2:22][N:23]([C:26](=[O:30])[C:27]([NH:1][C:2]2[CH:3]=[CH:4][C:5]3[O:10][CH2:9][C:8](=[O:11])[NH:7][C:6]=3[CH:12]=2)=[O:28])[CH2:24][CH2:25]1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

참가 물질

4

반응물 2

HCID 27636816-amino-3,4-dihydro-2H-1,4-benzoxazin-3-oneHCID 16110264(4-Benzylpiperidin-1-yl)oxoacetic acid

생성물 1

HCID 691004892-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(3-oxo-3,4-dihydro-2H-benzo [1,4]oxazin-6-yl)-acetamide

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

The title compound is prepared from 6-amino-4H-benzo[1,4]oxazin-3-one and (4-benzyl-piperidin-1-yl)-oxo-acetic acid (Example 5b) according to the method described in Example 1c. Melting Point: 186-187° C. (diethylether)

출처 및 근거

ORD 기록
ord-4c286ce20fe04e81a5ec7b4126a7b0b2
출처 데이터셋
uspto-grants-2008_10
특허 번호
US07435744B2

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