Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115020Generated: October 26, 2026

4-(4-Fluoro-benzyl)-piperidine → 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-acetamide

https://huagongshe.com/reaction/2115020

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Fluoro-benzyl)-piperidineHCID 3699841—
ReactantN-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-oxalamic acidHCID 53306726—
SolventDiethyl EtherHCID 3283—
Product2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-acetamideHCID 10136455—

Reaction Steps

The title compound is prepared from N-(2-oxo-2,3-dihydro-benzothiazol-6-yl)-oxalamic acid (Example 61b) and 4-(4-fluoro-benzyl)-piperidine according to the method described in Example 1c. Melting Point: 223.5-225.5° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-f34490ed4bc24407ae14335bbc873377
Source noteuspto-grants-2008_10