(4-Benzylpiperidin-1-yl)oxoacetic acid → HCID 86593928, compound

HRID 2115025Notes

Reaction equation

HRID 2115025 reaction equation
[NH2:1][C:2]1[CH:12]=[CH:11][C:5]2[NH:6][C:7](=[S:10])[CH2:8][O:9][C:4]=2[CH:3]=1.[CH2:13]([CH:20]1[CH2:25][CH2:24][N:23]([C:26](=[O:30])[C:27](O)=[O:28])[CH2:22][CH2:21]1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(OCC)C>[CH2:13]([CH:20]1[CH2:21][CH2:22][N:23]([C:26](=[O:30])[C:27]([NH:1][C:2]2[CH:12]=[CH:11][C:5]3[NH:6][C:7](=[S:10])[CH2:8][O:9][C:4]=3[CH:3]=2)=[O:28])[CH2:24][CH2:25]1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 16110264(4-Benzylpiperidin-1-yl)oxoacetic acidHCID 86593929HCID 86593929, compound

Product 1

HCID 86593928HCID 86593928, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 7-amino-4H-benzo[1,4]oxazin-3-thione and (4-benzyl-piperidin-1-yl)-oxo-acetic acid (Example 5b) according to the method described in Example 1c. Melting Point: 193-196° C. (diethylether)

Sources & evidence

ORD record
ord-f875a3fa60b94cc6a3e104901e7c6b49
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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