4-Nitroaniline → HCID 16804368, compound

HRID 2115027Notes

Reaction equation

HRID 2115027 reaction equation
[CH2:1]([CH:8]1[CH2:13][CH2:12][N:11]([C:14](=[O:18])[C:15]([OH:17])=O)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:19]([C:22]1[CH:28]=[CH:27][C:25]([NH2:26])=[CH:24][CH:23]=1)([O-:21])=[O:20]>C(OCC)C>[CH2:1]([CH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:18])[C:15]([NH:26][C:25]2[CH:27]=[CH:28][C:22]([N+:19]([O-:21])=[O:20])=[CH:23][CH:24]=2)=[O:17])[CH2:12][CH2:13]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 74754-NitroanilineHCID 16110264(4-Benzylpiperidin-1-yl)oxoacetic acid

Product 1

HCID 16804368HCID 16804368, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from (4-benzyl-piperidin-1-yl)-oxo-acetic acid (Example 5b) and 4-nitroaniline (Aldrich) according to the method described in Example 1c. Melting Point: 162-165° C. (diethylether)

Sources & evidence

ORD record
ord-873547ac113641ea9f8d21846bd07169
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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