4-Bromoaniline → HCID 69100517, compound

HRID 2115039Notes

Reaction equation

HRID 2115039 reaction equation
[CH2:1]([CH:8]1[CH2:13][CH2:12][N:11]([C:14](=[O:18])[C:15]([OH:17])=O)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:19][C:20]1[CH:26]=[CH:25][C:23]([NH2:24])=[CH:22][CH:21]=1>C(OCC)C>[CH2:1]([CH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:18])[C:15]([NH:24][C:23]2[CH:25]=[CH:26][C:20]([Br:19])=[CH:21][CH:22]=2)=[O:17])[CH2:12][CH2:13]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 78074-BromoanilineHCID 16110264(4-Benzylpiperidin-1-yl)oxoacetic acid

Product 1

HCID 69100517HCID 69100517, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from (4-benzyl-piperidin-1-yl)-oxo-acetic acid (Example 5b) and 4-bromo-aniline (Aldrich) according to the method described in Example 1c. Melting Point: 131-132° C. (diethylether)

Sources & evidence

ORD record
ord-ab29add7d6de49baa272764021a16122
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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