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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115042Generated: October 25, 2026

p-Toluidine → 2-(4-Benzyl-piperidin-1-yl)-N-(4-methyl-phenyl)-2-oxo-acetamide

https://huagongshe.com/reaction/2115042

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant(4-Benzylpiperidin-1-yl)oxoacetic acidHCID 16110264—
SolventDiethyl EtherHCID 3283—
Product2-(4-Benzyl-piperidin-1-yl)-N-(4-methyl-phenyl)-2-oxo-acetamideHCID 44901907—

Reaction Steps

The title compound is prepared from (4-benzyl-piperidin-1-yl)-oxo-acetic acid (Example 5b) and 4-methyl-aniline (Aldrich) according to the method described in Example 1c. Melting Point: 115-117° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-b75ebf04f5774de8a77fdfc9d5b78ede
Source noteuspto-grants-2008_10