HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitroaniline → 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(4-nitro-phenyl)-2-oxo-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitroaniline | HCID 7475 | — |
| Reactant | [4-(4-Fluorobenzyl)piperidin-1-yl](oxo)acetic acid | HCID 51342220 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(4-nitro-phenyl)-2-oxo-acetamide | HCID 69100691 | — |
Reaction Steps
The title compound is prepared from [4-(4-fluoro-benzyl)-piperidine-1-yl]-oxo-acetic acid (Example 1b) and 4-nitro-aniline (Aldrich) according to the method described in Example 1c. Melting Point: 157-159° C. (diethylether)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-546842aa5e15439ca911aa46e770a29f |
| Source note | uspto-grants-2008_10 |