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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115048Generated: October 31, 2026

p-Toluidine → 2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(4-methyl-phenyl)-2-oxo-acetamide

https://huagongshe.com/reaction/2115048

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant[4-(4-Fluorobenzyl)piperidin-1-yl](oxo)acetic acidHCID 51342220—
SolventDiethyl EtherHCID 3283—
Product2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-N-(4-methyl-phenyl)-2-oxo-acetamideHCID 69099970—

Reaction Steps

The title compound is prepared from [4-(4-fluoro-benzyl)-piperidin-1-yl]-oxo-acetic acid (Example 1b) and 4-methyl-aniline (Aldrich) according to the method described in Example 94. Melting Point: 125-126° C. (diethylether

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-2684e4ad41b24756922974a949595da3
Source noteuspto-grants-2008_10