3-(Trifluoromethyl)aniline → HCID 44902753, compound

HRID 2115050Notes

Reaction equation

HRID 2115050 reaction equation
[CH2:1]([CH:8]1[CH2:13][CH2:12][N:11]([C:14](=[O:18])[C:15]([OH:17])=O)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:19][C:20]([F:29])([F:28])[C:21]1[CH:22]=[C:23]([CH:25]=[CH:26][CH:27]=1)[NH2:24]>CCCCCC>[CH2:1]([CH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:18])[C:15]([NH:24][C:23]2[CH:25]=[CH:26][CH:27]=[C:21]([C:20]([F:19])([F:28])[F:29])[CH:22]=2)=[O:17])[CH2:12][CH2:13]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 73753-(Trifluoromethyl)anilineHCID 16110264(4-Benzylpiperidin-1-yl)oxoacetic acid

Product 1

HCID 44902753HCID 44902753, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

The title compound is prepared from (4-benzyl-piperidin-1-yl)-oxoacetic acid (Example 5b) and 3-(trifluoromethyl)-aniline (Aldrich) according to the method described in Example 1c. Melting Point: 87-89° C. (hexane)

Sources & evidence

ORD record
ord-f873b1bdac1b4d4a9cc1944771a97d2d
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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