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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115058Generated: November 3, 2026

Benzaldehyde → N-(4-Benzylamino-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-2-oxo-acetamide

https://huagongshe.com/reaction/2115058

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantN-(4-Amino-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-2-oxo-acetamideHCID 69100149—
SolventDiethyl EtherHCID 3283—
ProductN-(4-Benzylamino-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-2-oxo-acetamideHCID 69100195—

Reaction Steps

The title compound is prepared from N-(4-amino-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-2-oxo-acetamide (Example 104) and benzaldehyde according to the method described in Example 82. Melting Point: 145-148° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-44305ed7f7e3424a9847d3c0346ac74e
Source noteuspto-grants-2008_10