Diethyl Ether → HCID 10200583, compound

HRID 2115059Notes

Reaction equation

HRID 2115059 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])C2.[CH3:12][C:13]1[CH:30]=[CH:29][C:16]([CH2:17][CH:18]2[CH2:23][CH2:22][N:21]([C:24](=[O:28])[C:25]([OH:27])=O)[CH2:20][CH2:19]2)=[CH:15][CH:14]=1.C([O:33]CC)C>>[CH3:12][C:13]1[CH:14]=[CH:15][C:16]([CH2:17][CH:18]2[CH2:19][CH2:20][N:21]([C:24](=[O:28])[C:25]([NH:1][C:2]3[CH:10]=[CH:9][C:8]4[NH:7][C:6](=[O:11])[O:33][C:4]=4[CH:3]=3)=[O:27])[CH2:22][CH2:23]2)=[CH:29][CH:30]=1

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 27732135-Amino-2-oxindoleHCID 69100073[4-(4-Methyl-benzyl)-piperidin-1-yl)-oxo-acetic acid

Product 1

HCID 10200583HCID 10200583, compound

Procedure

The title compound is prepared from 5-amino-1,3-dihydro-indol-2-one and [4-(4-methyl-benzyl)-piperidin-1-yl)-oxo-acetic acid according to the method described in Example 1c. Melting Point: 216-220° C. (diethylether)

Sources & evidence

ORD record
ord-3c352830e0724cc6bc60a3ad58d76bf4
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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