4-((4-Methoxyphenyl)methyl)piperidine → N-(4-Methanesulfonylamino-phenyl)-2-[4-[4-methoxy-benzyl)-piperidin-1-yl]-2-oxo-acetamide

HRID 2115062Notes

Reaction equation

HRID 2115062 reaction equation
[CH3:1][S:2]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:13](=[O:17])[C:14]([OH:16])=O)=[CH:8][CH:7]=1)(=[O:4])=[O:3].[CH3:18][O:19][C:20]1[CH:32]=[CH:31][C:23]([CH2:24][CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)=[CH:22][CH:21]=1>C(OCC)C>[CH3:1][S:2]([NH:5][C:6]1[CH:7]=[CH:8][C:9]([NH:12][C:13](=[O:17])[C:14]([N:28]2[CH2:29][CH2:30][CH:25]([CH2:24][C:23]3[CH:22]=[CH:21][C:20]([O:19][CH3:18])=[CH:32][CH:31]=3)[CH2:26][CH2:27]2)=[O:16])=[CH:10][CH:11]=1)(=[O:3])=[O:4]

Participants

4

Reactant 2

HCID 37327404-((4-Methoxyphenyl)methyl)piperidineHCID 69100089N-(4-methanesulfonylamino-phenyl)-oxalamic acid

Product 1

HCID 69100193N-(4-Methanesulfonylamino-phenyl)-2-[4-[4-methoxy-benzyl)-piperidin-1-yl]-2-oxo-acetamide

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from N-(4-methanesulfonylamino-phenyl)-oxalamic acid and 4-(4-methoxy-benzyl)-piperidine according to the method described in Example 1c. Melting Point: 206-208° C. (diethylether)

Sources & evidence

ORD record
ord-95c625ef8fb0459d91e48fce6268b3f2
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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