5-Aminoisatin → HCID 69100735, compound

HRID 2115071Notes

Reaction equation

HRID 2115071 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=[O:12].[CH2:13]([CH:20]1[CH2:25][CH2:24][N:23]([C:26](=[O:30])[C:27](O)=[O:28])[CH2:22][CH2:21]1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(OCC)C>[CH2:13]([CH:20]1[CH2:21][CH2:22][N:23]([C:26](=[O:30])[C:27]([NH:1][C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[NH:7][C:6](=[O:11])[C:5]3=[O:12])=[O:28])[CH2:24][CH2:25]1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 118193465-AminoisatinHCID 16110264(4-Benzylpiperidin-1-yl)oxoacetic acid

Product 1

HCID 69100735HCID 69100735, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 5-amino-1H-indole-2,3-dion [Helv. Chim-Acta 19, 1327. (1936)] and (4-benzyl-piperidin-1-yl)-oxo-acetic-acid (Example 5b) according to the method described in Example 1c. Melting Point: 234-236° C. (diethylether)

Sources & evidence

ORD record
ord-1f46b89a673e479d9ac2d0d4c31663ae
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

Loading…