5-Amino-2-hydroxybenzimidazole → HCID 69100236, compound

HRID 2115072Notes

Reaction equation

HRID 2115072 reaction equation
[CH3:1][C:2]1[CH:19]=[CH:18][C:5]([CH2:6][CH:7]2[CH2:12][CH2:11][N:10]([C:13](=[O:17])[C:14]([OH:16])=O)[CH2:9][CH2:8]2)=[CH:4][CH:3]=1.[NH2:20][C:21]1[CH:30]=[CH:29][C:24]2[NH:25][C:26](=[O:28])[NH:27][C:23]=2[CH:22]=1>C(OCC)C>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][CH:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:17])[C:14]([NH:20][C:21]3[CH:30]=[CH:29][C:24]4[NH:25][C:26](=[O:28])[NH:27][C:23]=4[CH:22]=3)=[O:16])[CH2:11][CH2:12]2)=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 667655-Amino-2-hydroxybenzimidazoleHCID 69100073[4-(4-Methyl-benzyl)-piperidin-1-yl)-oxo-acetic acid

Product 1

HCID 69100236HCID 69100236, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from [4-(4-methyl-benzyl)-piperidin-1-yl]-oxo-acetic acid (Example 119b) and 5-amino-1,3-dihydro-benzimidazole-2-one according to the method described in Example 1c. Melting Point: >280° C. (diethylether)

Sources & evidence

ORD record
ord-d9a5132b5ed042ce9dc75134e90b3cfb
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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