4-Benzylpiperidine → HCID 69101026, compound
Reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:14]=[C:13]2[C:9]([CH:10]=[N:11][NH:12]2)=[CH:8][CH:7]=1)=[O:4].[CH2:15]([CH:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>C(OCC)C>[CH2:15]([CH:22]1[CH2:27][CH2:26][N:25]([CH2:2][C:3]([NH:5][C:6]2[CH:14]=[C:13]3[C:9]([CH:10]=[N:11][NH:12]3)=[CH:8][CH:7]=2)=[O:4])[CH2:24][CH2:23]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The title compound is prepared from 2-chloro-N-(1H-indazol-6-yl)-acetamide (Example 149a) and 4-benzyl-piperidine according to the method described in Example 142b. Melting Point: 165-169° C. (diethylether)
Sources & evidence
- ORD record
- ord-df4b14baa8d94852ab11fa49691d2532
- Source dataset
- uspto-grants-2008_10
- Patent number
- US07435744B2
Reaction notes
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