4-(4-Fluoro-benzyl)-piperidine → HCID 178521185, compound

HRID 2115084Notes

Reaction equation

HRID 2115084 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:14]=[CH:13][C:9]2[NH:10][CH:11]=[N:12][C:8]=2[CH:7]=1)=[O:4].[F:15][C:16]1[CH:28]=[CH:27][C:19]([CH2:20][CH:21]2[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]2)=[CH:18][CH:17]=1>C(OCC)C>[F:15][C:16]1[CH:17]=[CH:18][C:19]([CH2:20][CH:21]2[CH2:22][CH2:23][N:24]([CH2:2][C:3]([NH:5][C:6]3[CH:14]=[CH:13][C:9]4[NH:10][CH:11]=[N:12][C:8]=4[CH:7]=3)=[O:4])[CH2:25][CH2:26]2)=[CH:27][CH:28]=1

Participants

4

Reactant 2

HCID 36998414-(4-Fluoro-benzyl)-piperidineHCID 178520802HCID 178520802, compound

Product 1

HCID 178521185HCID 178521185, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 2-chloro-N-(1H-benzimidazol-5-yl)-acetamide (Example 151 a) and 4-(4-fluoro-benzyl)-piperidine according to the method described in Example 142b. Melting Point: 203.5-204.5° C. (diethylether)

Sources & evidence

ORD record
ord-1e87b4372c7a4d9da8d54b679f605ffe
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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