4-(4-Fluoro-benzyl)-piperidine → HCID 69101185, compound

HRID 2115088Notes

Reaction equation

HRID 2115088 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:7]=[CH:8][C:9]2[O:14][CH2:13][C:12](=[O:15])[NH:11][C:10]=2[CH:16]=1)=[O:4].[F:17][C:18]1[CH:30]=[CH:29][C:21]([CH2:22][CH:23]2[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]2)=[CH:20][CH:19]=1>C(OCC)C>[F:17][C:18]1[CH:19]=[CH:20][C:21]([CH2:22][CH:23]2[CH2:24][CH2:25][N:26]([CH2:2][C:3]([NH:5][C:6]3[CH:7]=[CH:8][C:9]4[O:14][CH2:13][C:12](=[O:15])[NH:11][C:10]=4[CH:16]=3)=[O:4])[CH2:27][CH2:28]2)=[CH:29][CH:30]=1

Participants

4

Reactant 2

HCID 36998414-(4-Fluoro-benzyl)-piperidineHCID 242983102-chloro-N-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)acetamide

Product 1

HCID 69101185HCID 69101185, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 2-chloro-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-acetamide (Example 155a) and 4-(4-fluoro-benzyl)-piperidine according to the method described in Example 142b. Melting Point: 185-187° C. (diethylether)

Sources & evidence

ORD record
ord-3e67997874914e4b80142a740eca6177
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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