Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115089Generated: October 25, 2026

4-Phenoxypiperidine → 2-(4-Phenoxy-piperidin-1-yl)-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-acetamide

https://huagongshe.com/reaction/2115089

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PhenoxypiperidineHCID 18878—
Reactant2-chloro-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-acetamideHCID 24298282—
SolventDiethyl EtherHCID 3283—
Product2-(4-Phenoxy-piperidin-1-yl)-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-acetamideHCID 69100032—

Reaction Steps

The title compound is prepared from 2-chloro-N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazin-7-yl)-acetamide (Example 153a) and 4-phenoxy-piperidine according to the method described in Example 142b. Melting Point: 206-208° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-22c4391079c5435988d09d0f40b026d2
Source noteuspto-grants-2008_10