5-Amino-2-oxindole → HCID 69100348, compound

HRID 2115094Notes

Reaction equation

HRID 2115094 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2.Cl.[CH2:13]([CH:20]1[CH2:25][CH2:24][N:23]([CH:26]([CH3:30])[C:27](O)=[O:28])[CH2:22][CH2:21]1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(OCC)C>[CH2:13]([CH:20]1[CH2:21][CH2:22][N:23]([CH:26]([CH3:30])[C:27]([NH:1][C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[NH:7][C:6](=[O:11])[CH2:5]3)=[O:28])[CH2:24][CH2:25]1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 2

HCID 27732135-Amino-2-oxindoleHCID 52983846HCID 52983846, compound

Product 1

HCID 69100348HCID 69100348, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 5-amino-1,3-dihydro-indol-2-one and 2-(4-benzyl-piperidin-1-yl)-propionic acid hydrochloride (Example 161b) according to the method described in Example 161c. Melting Point: 153-155° C. (diethylether).

Sources & evidence

ORD record
ord-7bf00bd8c5cb41e38d78397bc0ad152a
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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