4-Benzylpiperidine → HCID 9925287, compound

HRID 2115118Notes

Reaction equation

HRID 2115118 reaction equation
[CH2:1]([CH:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:15][C:16]([NH:18][C:19]1[CH:28]=[CH:27][C:22]2[NH:23][C:24](=[O:26])[NH:25][C:21]=2[CH:20]=1)=[O:17]>C(OCC)C>[CH2:1]([CH:8]1[CH2:13][CH2:12][N:11]([CH2:15][C:16]([NH:18][C:19]2[CH:28]=[CH:27][C:22]3[NH:23][C:24](=[O:26])[NH:25][C:21]=3[CH:20]=2)=[O:17])[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 317384-BenzylpiperidineHCID 11130072-Chloro-N-(2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-acetamide

Product 1

HCID 9925287HCID 9925287, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 4-benzyl-piperidine and 2-chloro-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-acetamide according to the method described in Example 142b. Melting Point: 270° C. (diethylether

Sources & evidence

ORD record
ord-bd5bc0ce375d42c0b8a2ef03cce8c0e3
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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