Diethyl Ether → HCID 86593933, compound

HRID 2115124Notes

Reaction equation

HRID 2115124 reaction equation
[NH2:1][C:2]1[CH:12]=[CH:11][C:5]2[NH:6][C:7](=[O:10])[CH2:8][O:9][C:4]=2[CH:3]=1.Cl[CH2:14][C:15]([N:17]1[CH2:22][CH2:21][CH:20]([CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH2:19][CH2:18]1)=O.C([O:32]CC)C>>[CH2:23]([CH:20]1[CH2:21][CH2:22][N:17]([CH:15]([NH:1][C:2]2[CH:12]=[CH:11][C:5]3[NH:6][C:7](=[O:10])[CH2:8][O:9][C:4]=3[CH:3]=2)[CH:14]=[O:32])[CH2:18][CH2:19]1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 11296081-(4-Benzylpiperidin-1-yl)-2-chloroethan-1-oneHCID 27641827-amino-3,4-dihydro-2H-1,4-benzoxazin-3-one

Product 1

HCID 86593933HCID 86593933, compound

Procedure

The title compound is prepared from 7-amino-4H-benzo[1,4]oxazine-3-one and 2-chloro-1-(4-benzyl-piperidin-1-yl)-ethanone (Example 200a) according to the method described in Example 142b. Melting Point: 172-175° C. (diethylether).

Sources & evidence

ORD record
ord-fb06d37b874f434aa4104435bdd15e61
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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