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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2115128Generated: October 25, 2026

1-(4-Benzylpiperidin-1-yl)-2-chloroethan-1-one → 1-(4-Benzyl-piperidin-1-yl)-2-(2-oxo-2,3-dihydro-benzothiazol-6-yl-amino)-ethanone

https://huagongshe.com/reaction/2115128

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Benzylpiperidin-1-yl)-2-chloroethan-1-oneHCID 1129608—
Reactant2(3H)-Benzothiazolone, 6-amino-HCID 6453329—
SolventDiethyl EtherHCID 3283—
Product1-(4-Benzyl-piperidin-1-yl)-2-(2-oxo-2,3-dihydro-benzothiazol-6-yl-amino)-ethanoneHCID 69100897—

Reaction Steps

The title compound is prepared from 6-amino-3H-benzothiazole-2-one and 2-chloro-1-(4-benzyl-piperidin-1-yl)-ethanone (Example 200a) according to the method described in Example 206. Melting Point: 196-199° C. (diethylether)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07435744B2
Source datasetuspto-grants-2008_10
ORD IDord-b3440344a9e549249b43f1cce188927c
Source noteuspto-grants-2008_10