2(3H)-Benzothiazolone, 6-amino- → 1-(4-p-Tolyloxy-piperidin-1-yl)-2-(2-oxo-2,3-dihydro-benzothiazol-6-yl-amino)-ethanone

HRID 2115129Notes

Reaction equation

HRID 2115129 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]2[NH:6][C:7](=[O:9])[S:8][C:4]=2[CH:3]=1.Cl[CH2:13][C:14]([N:16]1[CH2:21][CH2:20][CH:19]([O:22][C:23]2[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][CH:24]=2)[CH2:18][CH2:17]1)=[O:15]>C(OCC)C>[C:26]1([CH3:29])[CH:25]=[CH:24][C:23]([O:22][CH:19]2[CH2:20][CH2:21][N:16]([C:14](=[O:15])[CH2:13][NH:1][C:2]3[CH:11]=[CH:10][C:5]4[NH:6][C:7](=[O:9])[S:8][C:4]=4[CH:3]=3)[CH2:17][CH2:18]2)=[CH:28][CH:27]=1

Participants

4

Reactant 2

HCID 64533292(3H)-Benzothiazolone, 6-amino-HCID 691003022-Chloro-1-(4-p-tolyloxy-piperidin-1-yl) ethanone

Product 1

HCID 691003981-(4-p-Tolyloxy-piperidin-1-yl)-2-(2-oxo-2,3-dihydro-benzothiazol-6-yl-amino)-ethanone

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 6-amino-3H-benzothiazole-2-one and 2-chloro-1-(4-p-tolyloxy-piperidin-1-yl)-ethanone according to the method described in Example 206. Melting Point: 189-191° C. (diethylether)

Sources & evidence

ORD record
ord-458df602f0e74b56baa88599151b8884
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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