HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminobenzonitrile → 4-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-ethylamino}-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminobenzonitrile | HCID 13396 | — |
| Reactant | 2-Chloro-1-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanone | HCID 69100056 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 4-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-oxo-ethylamino}-benzonitrile | HCID 69100934 | — |
Reaction Steps
The title compound is prepared from 4-amino-benzonitrile and 2-chloro-1-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanone (Example 197a) according to the method described in Example 206. Melting Point: 204-206° C. (diethylether)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435744B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-25c9f76708524bc6897f2cd744938c28 |
| Source note | uspto-grants-2008_10 |