Boron tribromide → HCID 69101047, compound

HRID 2115136Notes

Reaction equation

HRID 2115136 reaction equation
[CH2:1]([CH:8]1[CH2:13][CH2:12][N:11]([C:14](=[O:25])[CH2:15][NH:16][C:17]2[CH:22]=[CH:21][C:20]([O:23]C)=[CH:19][CH:18]=2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.B(Br)(Br)Br>C(OCC)C>[CH2:1]([CH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:25])[CH2:15][NH:16][C:17]2[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][CH:18]=2)[CH2:12][CH2:13]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 69100023HCID 69100023, compound

Product 1

HCID 69101047HCID 69101047, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 1-(4-benzyl-piperidin-1-yl)-2-(4-methoxy-phenylamino)-ethanone (Example 220) and boron tribromide according to the method described in Example 192. Melting Point: 138-140° C. (diethylether)

Sources & evidence

ORD record
ord-f49ce1a9266643768a9c55e17881e96c
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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