Boron tribromide → HCID 69101097, compound

HRID 2115137Notes

Reaction equation

HRID 2115137 reaction equation
[F:1][C:2]1[CH:26]=[CH:25][C:5]([CH2:6][CH:7]2[CH2:12][CH2:11][N:10]([C:13](=[O:24])[CH2:14][NH:15][C:16]3[CH:21]=[CH:20][C:19]([O:22]C)=[CH:18][CH:17]=3)[CH2:9][CH2:8]2)=[CH:4][CH:3]=1.B(Br)(Br)Br>C(OCC)C>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][CH:7]2[CH2:12][CH2:11][N:10]([C:13](=[O:24])[CH2:14][NH:15][C:16]3[CH:17]=[CH:18][C:19]([OH:22])=[CH:20][CH:21]=3)[CH2:9][CH2:8]2)=[CH:25][CH:26]=1

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 691001961-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-2-(4-methoxy-phenylamino)-ethanone

Product 1

HCID 69101097HCID 69101097, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 1-[4-(4-fluoro-benzyl)-piperidin-1-yl]-2-(4-methoxy-phenylamino)-ethanone (Example 219) and boron tribromide according to the method described in Example 192. Melting Point: 155-157° C. (diethylether)

Sources & evidence

ORD record
ord-a544e584e2a7466c8d2d7a63ad071a90
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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