6-amino-1,3-benzoxazol-2(3H)-one → HCID 9947259, compound

HRID 2115141Notes

Reaction equation

HRID 2115141 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]2[NH:6][C:7](=[O:9])[O:8][C:4]=2[CH:3]=1.Cl[CH2:13][C:14]([N:16]1[CH2:21][CH2:20][CH:19]([CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH2:18][CH2:17]1)=[O:15]>C(OCC)C>[CH2:22]([CH:19]1[CH2:18][CH2:17][N:16]([C:14](=[O:15])[CH2:13][NH:1][C:2]2[CH:11]=[CH:10][C:5]3[NH:6][C:7](=[O:9])[O:8][C:4]=3[CH:3]=2)[CH2:21][CH2:20]1)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

4

Reactant 2

HCID 8269896-amino-1,3-benzoxazol-2(3H)-oneHCID 11296081-(4-Benzylpiperidin-1-yl)-2-chloroethan-1-one

Product 1

HCID 9947259HCID 9947259, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The title compound is prepared from 6-amino-3H-benzoxazol-2-one and 2-chloro-1-(4-benzyl-piperidin-1-yl)-ethanone (Example 200a) according to the method described in Example 142b. Melting Point: 204-206° C. (diethylether)

Sources & evidence

ORD record
ord-a1b77dfc01fc4c649d5506c2e9b4d146
Source dataset
uspto-grants-2008_10
Patent number
US07435744B2

Reaction notes

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