7-amino-3,4-dihydro-2H-1,4-benzoxazin-3-one → 7-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-4H-benzo[1,4]oxazin-3-one

Participants

Role	Name	HCID	Charge
Reactant	7-amino-3,4-dihydro-2H-1,4-benzoxazin-3-one	HCID 2764182	—
Reactant	6-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-3h-benzoxazol-2-one	HCID 69099990	—
Solvent	Methanol	HCID 887	—
Product	7-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-2-oxo-ethylamino}-4H-benzo[1,4]oxazin-3-one	HCID 69100323	—

Reaction Steps

The title compound is prepared from 2-chloro-1-[4-(4-chloro-phenoxy)-piperidin-1-yl]-ethanone (Example 233) and 7-amino-4H-benzo[1,4]oxazin-3-one according to the method described in Example 206. Melting Point:207-210° C. (methanol)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07435744B2
Source dataset	uspto-grants-2008_10
ORD ID	ord-135410d446f74db6baf650c7c61d7020
Source note	uspto-grants-2008_10