HCID 69312743, compound → HCID 69314285, compound

Participants

Reaction Steps

Palladium-on-carbon (5%, 0.3 g) was added to a solution of 6-(2-(4-pentyl-2-fluorophenyl)ethenyl)-3,4-dihydrocoumarin (3.2 g) in ethanol (30 ml), and the mixture was stirred in a hydrogen atmosphere for 24 hours. The catalyst was removed from the reaction mixture by filtration, and the resulting solution was concentrated in vacuo and subjected to isolation and purification by silica gel column chromatography, thereby obtaining a while crystal (2.1 g) of a titled compound.

Provenance & Evidence