Dichloromethane → HCID 10193053, compound

HRID 2115275Notes

Reaction equation

HRID 2115275 reaction equation
ClCCl.[C:4]1([CH2:22][OH:23])[S:5][CH:6]=[C:7]2[C:13]=1[C:12]1[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=1[S:10][C:9]1[CH:18]=[CH:19][CH:20]=[CH:21][C:8]2=1>C(OCC)C>[C:4]1([CH:22]=[O:23])[S:5][CH:6]=[C:7]2[C:13]=1[C:12]1[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=1[S:10][C:9]1[CH:18]=[CH:19][CH:20]=[CH:21][C:8]2=1

Participants

4

Reactant 2

HCID 6344DichloromethaneHCID 10149515HCID 10149515, compound

Product 1

HCID 10193053HCID 10193053, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a dichloromethane solution of the alcohol 15 (3.0 mmoles in 40 ml) dipyridine-chromium-(VI)-oxide (pyridinyl dichromate, PDC, 0.006 mole) was added. The reaction mixture was stirred at room temperature for 18 hours. Diethyl ether (50 ml) was added to the reaction mixture and the thus diluted reaction mixture was purified on a Florisil column to give a yellow crystal product.

Workup

  1. customthe thus diluted reaction mixture
  2. customwas purified on a Florisil column
  3. customto give a yellow crystal product

Sources & evidence

ORD record
ord-e94f13bf1fe7442c8487af10d9b78b40
Source dataset
uspto-grants-2008_10
Patent number
US07435834B2

Reaction notes

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