tert-Butyl bromoacetate → [(4-tert-Butyl-benzenesulfonyl)-p-tolyl-amino]-acetic acid
Reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].Br[CH2:23][C:24]([O:26]C(C)(C)C)=[O:25]>>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([S:11]([N:14]([CH2:23][C:24]([OH:26])=[O:25])[C:15]2[CH:16]=[CH:17][C:18]([CH3:21])=[CH:19][CH:20]=2)(=[O:13])=[O:12])=[CH:9][CH:10]=1)([CH3:4])([CH3:3])[CH3:2]Participants
3
Procedure
prepared by reaction of 4-tert-butyl-N-p-tolyl-benzenesulfonamide with tert-butyl bromoacetate
Sources & evidence
- ORD record
- ord-60ee980197d546f893b553704d09738c
- Source dataset
- uspto-grants-2008_10
- Patent number
- US07435815B2
Reaction notes
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