tert-Butyl bromoacetate → [(4-tert-Butyl-benzenesulfonyl)-quinolin-6-yl-amino]-acetic acid

HRID 2115411Notes

Reaction equation

HRID 2115411 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[CH:16]=[C:17]3[C:22](=[CH:23][CH:24]=2)[N:21]=[CH:20][CH:19]=[CH:18]3)(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].Br[CH2:26][C:27]([O:29]C(C)(C)C)=[O:28]>>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([S:11]([N:14]([CH2:26][C:27]([OH:29])=[O:28])[C:15]2[CH:16]=[C:17]3[C:22](=[CH:23][CH:24]=2)[N:21]=[CH:20][CH:19]=[CH:18]3)(=[O:12])=[O:13])=[CH:9][CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 79177tert-Butyl bromoacetateHCID 3281411HCID 3281411, compound

Product 1

HCID 58978463[(4-tert-Butyl-benzenesulfonyl)-quinolin-6-yl-amino]-acetic acid

Procedure

prepared by reaction of 4-tert-butyl-N-quinolin-6-yl-benzenesulfonamide with tert-butyl bromoacetate

Sources & evidence

ORD record
ord-4b5e04619cf746e0a98c5ba7ae4eaab0
Source dataset
uspto-grants-2008_10
Patent number
US07435815B2

Reaction notes

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