Benzylethanolamine → N-Benzyl-2-[(4-tert-butyl-benzenesulfonyl)-(1H-indazol-6-yl)-amino]-N-(2-hydroxy-ethyl)-acetamide

HRID 2115472Notes

Reaction equation

HRID 2115472 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]([CH2:24][C:25](O)=[O:26])[C:15]2[CH:23]=[C:22]3[C:18]([CH:19]=[N:20][NH:21]3)=[CH:17][CH:16]=2)(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH2:28]([NH:35][CH2:36][CH2:37][OH:38])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[CH2:28]([N:35]([CH2:36][CH2:37][OH:38])[C:25](=[O:26])[CH2:24][N:14]([S:11]([C:8]1[CH:7]=[CH:6][C:5]([C:1]([CH3:3])([CH3:4])[CH3:2])=[CH:10][CH:9]=1)(=[O:13])=[O:12])[C:15]1[CH:23]=[C:22]2[C:18]([CH:19]=[N:20][NH:21]2)=[CH:17][CH:16]=1)[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1

Participants

3

Reactant 2

HCID 4348BenzylethanolamineHCID 58978462[(4-tert-Butyl-benzenesulfonyl)-(1H-indazol-6-yl)-amino]-acetic acid

Product 1

HCID 11756445N-Benzyl-2-[(4-tert-butyl-benzenesulfonyl)-(1H-indazol-6-yl)-amino]-N-(2-hydroxy-ethyl)-acetamide

Procedure

prepared by reaction of [(4-tert-butyl-benzenesulfonyl)-(1H-indazol-6-yl)-amino]-acetic acid with 2-benzylamino-ethanol

Sources & evidence

ORD record
ord-1ae0c6d77d4f4451b1bc5bbb55406f5f
Source dataset
uspto-grants-2008_10
Patent number
US07435815B2

Reaction notes

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