Nsc65650 → 2-[(4-tert-Butyl-benzenesulfonyl)-p-tolyl-amino]-N-(3-hydroxy-propyl)-N-pyridin-2-ylmethyl-acetamide

HRID 2115479Notes

Reaction equation

[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]([CH2:22][C:23]([OH:25])=O)[C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[N:26]1[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=1[CH2:32][NH:33][CH2:34][CH2:35][CH2:36][OH:37]>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]([C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)[CH2:22][C:23]([N:33]([CH2:34][CH2:35][CH2:36][OH:37])[CH2:32][C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][N:26]=2)=[O:25])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:3])([CH3:4])[CH3:2]

Participants

Reactant 2

HCID 248485Nsc65650

HCID 58978369[(4-tert-Butyl-benzenesulfonyl)-p-tolyl-amino]-acetic acid

Product 1

HCID 589784032-[(4-tert-Butyl-benzenesulfonyl)-p-tolyl-amino]-N-(3-hydroxy-propyl)-N-pyridin-2-ylmethyl-acetamide

Procedure

prepared by reaction of [(4-tert-butyl-benzenesulfonyl)-p-tolyl-amino]-acetic acid with 3-[(pyridin-2-ylmethyl)-amino]-propan-1-ol

Sources & evidence

ORD record: ord-4f3b269f99964195b85bd5b094299851
Source dataset: uspto-grants-2008_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07435815B2

Reaction notes

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