Nsc65650 → 2-[(4-tert-Butyl-benzenesulfonyl)-quinolin-6-yl-amino]-N-(3-hydroxy-propyl)-N-pyridin-2-ylmethyl-acetamide

HRID 2115488Notes

Reaction equation

HRID 2115488 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]([CH2:25][C:26](O)=[O:27])[C:15]2[CH:16]=[C:17]3[C:22](=[CH:23][CH:24]=2)[N:21]=[CH:20][CH:19]=[CH:18]3)(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[N:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[CH2:35][NH:36][CH2:37][CH2:38][CH2:39][OH:40]>>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([S:11]([N:14]([C:15]2[CH:16]=[C:17]3[C:22](=[CH:23][CH:24]=2)[N:21]=[CH:20][CH:19]=[CH:18]3)[CH2:25][C:26]([N:36]([CH2:37][CH2:38][CH2:39][OH:40])[CH2:35][C:30]2[CH:31]=[CH:32][CH:33]=[CH:34][N:29]=2)=[O:27])(=[O:12])=[O:13])=[CH:9][CH:10]=1)([CH3:2])([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 248485Nsc65650HCID 58978463[(4-tert-Butyl-benzenesulfonyl)-quinolin-6-yl-amino]-acetic acid

Product 1

HCID 589783522-[(4-tert-Butyl-benzenesulfonyl)-quinolin-6-yl-amino]-N-(3-hydroxy-propyl)-N-pyridin-2-ylmethyl-acetamide

Procedure

prepared by reaction of [(4-tert-butyl-benzenesulfonyl)-quinolin-6-yl-amino]-acetic acid with 3-[(pyridin-2-ylmethyl)-amino]-propan-1-ol

Sources & evidence

ORD record
ord-1aec4199e3bd4240a84fcc304a94f545
Source dataset
uspto-grants-2008_10
Patent number
US07435815B2

Reaction notes

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