N-((3-Methylphenyl)methyl)cyclopropanamine → 2-[(4-tert-Butyl-benzenesulfonyl)-quinolin-6-yl-amino]-N-cyclopropyl-N-(3-methyl-benzyl)-acetamide

HRID 2115501Notes

Reaction equation

HRID 2115501 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]([CH2:25][C:26](O)=[O:27])[C:15]2[CH:16]=[C:17]3[C:22](=[CH:23][CH:24]=2)[N:21]=[CH:20][CH:19]=[CH:18]3)(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH:29]1([NH:32][CH2:33][C:34]2[CH:39]=[CH:38][CH:37]=[C:36]([CH3:40])[CH:35]=2)[CH2:31][CH2:30]1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]([C:15]2[CH:16]=[C:17]3[C:22](=[CH:23][CH:24]=2)[N:21]=[CH:20][CH:19]=[CH:18]3)[CH2:25][C:26]([N:32]([CH:29]2[CH2:31][CH2:30]2)[CH2:33][C:34]2[CH:39]=[CH:38][CH:37]=[C:36]([CH3:40])[CH:35]=2)=[O:27])(=[O:12])=[O:13])=[CH:7][CH:6]=1)([CH3:3])([CH3:4])[CH3:2]

Participants

3

Reactant 2

HCID 16776498N-((3-Methylphenyl)methyl)cyclopropanamineHCID 58978463[(4-tert-Butyl-benzenesulfonyl)-quinolin-6-yl-amino]-acetic acid

Product 1

HCID 589783302-[(4-tert-Butyl-benzenesulfonyl)-quinolin-6-yl-amino]-N-cyclopropyl-N-(3-methyl-benzyl)-acetamide

Procedure

prepared by reaction of [(4-tert-butyl-benzenesulfonyl)-quinolin-6-yl-amino]-acetic acid with cyclopropyl-(3-methyl-benzyl)-amine

Sources & evidence

ORD record
ord-1795a68703ec472f9a33c98f92a9117a
Source dataset
uspto-grants-2008_10
Patent number
US07435815B2

Reaction notes

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