N-((3-Methylphenyl)methyl)cyclopropanamine → 2-((4-tert-Butyl-benzenesulfonyl)-{[cyclopropyl-(3-methyl-benzyl)-carbamoyl]-methyl}-amino)-benzamide

HRID 2115504Notes

Reaction equation

HRID 2115504 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([N:14]([CH2:24][C:25]([OH:27])=O)[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[C:21](=[O:23])[NH2:22])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH:28]1([NH:31][CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[C:35]([CH3:39])[CH:34]=2)[CH2:30][CH2:29]1>>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([S:11]([N:14]([CH2:24][C:25](=[O:27])[N:31]([CH:28]2[CH2:30][CH2:29]2)[CH2:32][C:33]2[CH:38]=[CH:37][CH:36]=[C:35]([CH3:39])[CH:34]=2)[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[C:21]([NH2:22])=[O:23])(=[O:12])=[O:13])=[CH:9][CH:10]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 16776498N-((3-Methylphenyl)methyl)cyclopropanamineHCID 58978332[(4-tert-Butyl-benzenesulfonyl)-(2-carbamoyl-phenyl)-amino]-acetic acid

Product 1

HCID 589783552-((4-tert-Butyl-benzenesulfonyl)-{[cyclopropyl-(3-methyl-benzyl)-carbamoyl]-methyl}-amino)-benzamide

Procedure

prepared by reaction of [(4-tert-butyl-benzenesulfonyl)-(2-carbamoyl-phenyl)-amino]-acetic acid with cyclopropyl-(3-methyl-benzyl)-amine

Sources & evidence

ORD record
ord-fbfcb949d8914af08b76db00be97a1b2
Source dataset
uspto-grants-2008_10
Patent number
US07435815B2

Reaction notes

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