3-(Ethylamino)propionitrile → N-(2-Cyano-ethyl)-N-ethyl-2-[(6-methoxy-pyridin-3-yl)-(toluene-2-sulfonyl)-amino]-acetamide

HRID 2115533Notes

Reaction equation

HRID 2115533 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([N:9]([CH2:20][C:21]([OH:23])=O)[S:10]([C:13]2[C:14]([CH3:19])=[CH:15][CH:16]=[CH:17][CH:18]=2)(=[O:12])=[O:11])=[CH:5][CH:4]=1.[CH2:24]([NH:26][CH2:27][CH2:28][C:29]#[N:30])[CH3:25]>>[C:29]([CH2:28][CH2:27][N:26]([CH2:24][CH3:25])[C:21](=[O:23])[CH2:20][N:9]([C:6]1[CH:7]=[N:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)[S:10]([C:13]1[C:14]([CH3:19])=[CH:15][CH:16]=[CH:17][CH:18]=1)(=[O:12])=[O:11])#[N:30]

Participants

3

Reactant 2

HCID 2489613-(Ethylamino)propionitrileHCID 58978342N-(6-Methoxy-3-pyridinyl)-N-[(2-methylphenyl)sulfonyl]glycine

Product 1

HCID 58978398N-(2-Cyano-ethyl)-N-ethyl-2-[(6-methoxy-pyridin-3-yl)-(toluene-2-sulfonyl)-amino]-acetamide

Procedure

prepared by reaction of [(6-methoxy-pyridin-3-yl)-(toluene-2-sulfonyl)-amino]-acetic acid with 3-ethylamino-propionitrile LC-MS: rt=0.91 min, 417 (M+1, ES+).

Workup

  1. customrt=0.91 min, 417 (M+1, ES+)

Sources & evidence

ORD record
ord-62b1ea149a9a407e8d1cf591cef365bf
Source dataset
uspto-grants-2008_10
Patent number
US07435815B2

Reaction notes

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