Ethanol, 2-((2-pyridinylmethyl)amino)- → N-(2-Hydroxy-ethyl)-2-[(5-isopropyl-pyridine-2-sulfonyl)-(6-methoxy-pyridin-3-yl)-amino]-N-pyridin-2-ylmethyl-acetamide

HRID 2115564Notes

Reaction equation

HRID 2115564 reaction equation
[CH:1]([C:4]1[CH:5]=[CH:6][C:7]([S:10]([N:13]([CH2:22][C:23](O)=[O:24])[C:14]2[CH:15]=[N:16][C:17]([O:20][CH3:21])=[CH:18][CH:19]=2)(=[O:12])=[O:11])=[N:8][CH:9]=1)([CH3:3])[CH3:2].[N:26]1[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=1[CH2:32][NH:33][CH2:34][CH2:35][OH:36]>>[OH:36][CH2:35][CH2:34][N:33]([CH2:32][C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][N:26]=1)[C:23](=[O:24])[CH2:22][N:13]([S:10]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:9][N:8]=1)(=[O:12])=[O:11])[C:14]1[CH:15]=[N:16][C:17]([O:20][CH3:21])=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 81135Ethanol, 2-((2-pyridinylmethyl)amino)-HCID 58978467[(5-Isopropyl-pyridine-2-sulfonyl)-(6-methoxy-pyridin-3-yl)-amino]-acetic acid

Product 1

HCID 58978465N-(2-Hydroxy-ethyl)-2-[(5-isopropyl-pyridine-2-sulfonyl)-(6-methoxy-pyridin-3-yl)-amino]-N-pyridin-2-ylmethyl-acetamide

Procedure

prepared by reaction of [(5-isopropyl-pyridine-2-sulfonyl)-(6-methoxy-pyridin-3-yl)-amino]-acetic acid with 2-[(pyridin-2-ylmethyl)-amino]-ethanol

Sources & evidence

ORD record
ord-dde4f4b729aa48e0bf1f449f3cdf7d61
Source dataset
uspto-grants-2008_10
Patent number
US07435815B2

Reaction notes

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