HCID 67520578, compound → HCID 67520412, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of methyl 7-(6,7-dimethoxyquinolin-4-yloxy)-2-naphthoate (Step c, 0.809 g, 2.08 mmol) in EtOH (10 mL), 1N NaOH (3 mL) was added. The solution was stirred at 70° C. for 2 h. The reaction was cooled to RT and concentrated in vacuo. The crude material was taken up in water (50 mL) and acidified to pH=3 with 1N HCl. The solid was filtered and dried in vacuo. MS (ESI, pos. ion) m/z: 376.1 (M+1).

Provenance & Evidence