Chlorothymol → HCID 86599067, compound

Participants

Reaction Steps

Treatment of 4-chloro-2-isopropyl-5-methylphenol (10.00 g, 0.054 mol) with potassium carbonate (29.94 g, 0.217 mol) and allyl bromide (7.86 g, 0.065 mol), followed by refluxing the resultant allyl ether in mesitylene generally according to the procedure described for Intermediate 8 provided 8.92 g (73%) of 2-allyl-4-chloro-6-isopropyl-3-methylphenol as a colorless oil. Rf=0.85 (silica, ethyl acetate:hexanes 1:9); Anal. calcd. for C13H17ClO: C, 69.48; H, 7.62. Found: C, 69.87; H, 7.43.

Provenance & Evidence