HuagongsheHuagongshe Chemistry Print Report · For research reference only
Mesitylene → 6-Bromo-3-fluoro-2-(2-propen-1-yl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Mesitylene | HCID 7947 | — |
| Reactant | 1-Bromo-2-allyloxy-4-fluorobenzene | HCID 66654640 | — |
| Product | 6-Bromo-3-fluoro-2-(2-propen-1-yl)phenol | HCID 68962539 | 95% |
Reaction Steps
Treatment of 2-(allyloxy)-1-bromo-4-fluorobenzene (12.00 g, 0.052 mol) in refluxing mesitylene generally according to the reaction procedure described for Intermediate 8 provided 11.5 g (95%) of 2-allyl-6-bromo-3-fluorophenol as a pale yellow oil. Rf=0.48 (silica, ethyl acetate:hexanes 1:4); Anal. calcd. for C9H8BrFO: C, 46.78; H, 3.49. Found: C, 47.59; H, 3.47.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435837B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-d8946032437a4924a592cac15c85b8f9 |
| Source note | uspto-grants-2008_10 |