HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,5-Dimethylphenyl)boronic acid → HCID 86599150, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,5-Dimethylphenyl)boronic acid | HCID 2734347 | — |
| Reactant | (7-Bromo-2,3-dihydro-1-benzofuran-2-yl)methyl 4-methylbenzenesulfonate | HCID 58747572 | — |
| Product | HCID 86599150 | HCID 86599150 | 81% |
Reaction Steps
Treatment of (±)-(7-bromo-2,3-dihydro-1-benzofuran-2-yl)methyl 4-methylbenzenesulfonate (0.50 g, 1.305 mmol) with (2,5-dimethylphenyl)boronic acid (0.294 g, 1.96 mmol) generally according to the procedure described for Intermediate 184 provided 0.430 g (81%) of (±)-[7-(2,5-dimethylphenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonate as a white solid. Rf=0.43 (silica, ethyl acetate:hexanes 1:4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07435837B2 |
| Source dataset | uspto-grants-2008_10 |
| ORD ID | ord-a2bb785980984506bd9963c862799b09 |
| Source note | uspto-grants-2008_10 |